• The natural, undisturbed by humans ecological communities of biological species create and further control their environment. They maintain it in a state optimal for the whole community and compensate for all deviations from that optimum up to a certain threshold. Such biotic regulation occurs on both local and global scales.

• Biotic regulation is performed by complex co-ordinated functioning of all species in the natural ecological community. The information needed to ensure such functioning is contained in the genomes of species. This information is prevented from decay in the course of natural stabilising selection. Evolution proceeds in the direction of enhancing the regulatory potential of the community.

• Anthropogenic transformation of natural ecosystems leads to disintegration of the corresponding ecological communities and destroys their regulatory potential. Anthropogenically disturbed and artificially created biological systems are deprived of regulatory abilities. On the contrary, such systems act as powerful destabilisers of the environment. This renders the environment unstable both on a local and global scale and may ultimately lead to complete degradation of suitable for life environmental conditions.

• The contemporary favourable for life environment and climate of Earth are physically unstable. Without stabilising impact of the natural biota they would rapidly degrade to a state unfit for life. The major challenge for the modern natural science is therefore to quantify the necessary global area that should be exempted from anthropogenic activities and given back to natural ecosystems, if the long-term stability of favourable for life environment and climate on Earth is to be restored.